For any engine running FI , stock or near stock cam and sub 10 to 1 compression. The stock spark marker is hard to beat.
MSD and others got there rep in the days of carbed engines with unreliably air/fuel mixes, high(er) compression engines that came with points and condensers or EI that were not much better. They often ran .55 inch plug gaps that didn't help a bit.
ANY help in the firering that mess was welcome and worth the money. Now a days, not so much.