Like most friends, you have to spend time with them. Like was said, externally, a lot can be different - but - lots of folks swap stuff from HO to non-HO and make it work.
Engine internals are a toss up at factory horsepower levels, but with judicious choices, they can at least add reassurance to a stroker build or higher horsepower motor. Searching sites like here, the jeep stoker motor forum, and others will get you all the greasy details. It's easy to find enough to print an entire ream of paper.