one bottle of bg44k and a replacement ECM (488) and still no dice. Will run smooth for a few seconds and will die. if any throttle is applied it sputters, back fires and dies.... cleaned all grounds to bright shiny metal, they might as well be chromed at this point.
You could still have a resistance problem with a damaged wire. This was why I replaced the last several inches on a couple of my ground wires that showed damage near the ends.
A wiring resistance problem would be consistent with your problem. A wire that already has a resistance problem gets hotter and the resistance increases. The challenge is finding that particular wire. I had one that took me months to find. It was on my '90 GTA, and the problem was with a single injector that would short out internally and pull down the entire bank (batch fire). And of course it only did this when I had driven away from home. I found that one by disconnecting the injector to test with a noid light.
Having gone through all your grounds, did you notice any wires that felt hard and inflexible? That is a sign of excessive heat. I would start by checking all the ignition related wires. Make sure they are still flexible and that there is no damage to the insulation. Move wiring around temporarily just to see if being pulled away from something solves your problem. (BTW, have you made sure your coil wire is not compromised in any way? Random thought, can't keep track of what all you have/haven't done. The coil wire is one of those I would be moving for testing purposes.)
I would also closely inspect any places where wires get close to metal. Again, inspect the insulation.
Another place to look is fuses and relays. Pull them one at a time and inspect the spade terminals. They should be relatively clean. A brass wire brush on any that have surface corrosion would be good.
I would also look under the dash. Has anyone ever spliced into the "ignition on" circuit for the addition of aftermarket stereo equipment, an alarm or some other such thing? I never trust any of those people's crimp connections. Don't go tugging on any of those wires unless you are prepared to make some splice repairs, but if you find suspect wiring down there arm yourself with the right tools and go after those connections. (Right tools in my world require solder and heat shrink.)
It sounds to me like you have something electrical that is heating up quickly and probably shorting out, or at least providing such a high resistance that something ceases to function. It could be in the vehicle wiring, or it could be internal to a component (like my fuel injector). Besides the wiring check, I would be doing everything possible to monitor systems functions during failure. Watch fuel pressure and whatever you can manage to watch on a scan tool. Keep searching for clues. And let us know what you find.