Depends on the condition of the welder, the cord/breaker you are using, etc. If your welder has a heat/speed chart, consult it and go from there.
On my 220v snap-on, i use 3/3.3, but that'll mean absolutely nothing to you. Learning to dial in a mig welder is a big chunk of being able to mig weld, be patient untill you get it 100% they way you want before you weld on anything you care about, and if you plan on going upside down, or switching to thicker material, adjust accordingly.
As far as 75/25% gas flow, IIRC, i use 18-22 cfm, depending on where i am welding, and how much wind that area has.