The radiator should fit - just leave the Thermal Fan Switch in place (if going from RENIX to HO) or come up with a way to mount a new TFS somewhere else (if going HO to RENIX - usually, you move the thermostat housing over, which gives you a 3/8" NPT drilled & tapped hole. There are various Chevvy parts that will work.)
So, since you're going RENIX to HO, you can just leave the TFS in place and cut the wiring off (save it - it can come in handy as a pigtail for something else.) Check for transmission cooler fittings on the early radiator - it's possible that you've got it, and it just went unused. If you do not, add an external cooler and you're good (which is going to be a good deal cheaper than a new radiator.)