I've never replaced the oil pump, never had any issues. But I have had the seal start to leak again in fairly short order, like a few months. I've changed the same seal on numerous occasions, never noticed the rear main bolts being loose, I probably would have noticed when I removed them again.
I typically clean the bolt and block thread holes with brake cleaner and add a dab of blue Loc Tite. And torque to spec., the Loc Tite likely acts like a thread lub and the actual torque is increased a bit.
I have had issues disturbing the junk that builds up inside a motor. Some of it is jelly like. The oil passages aren't that large and my oil pressure has done odd things for awhile, like too high and a jumpy needle. It all seemed to eventually work itself out after awhile. But it always made me nervous. I do clean up the pan good and do the best I can with the oil pump pickup.
One of these days I'm going to remove the pump and check the clearances. The oil pump gear teeth have never shown much wear on the 4.0 pumps I've looked in. I get the feeling most of the wear is on the gear sides and possibly removing the pump gasket and replacing it with a thinner one, could increase efficiency. The oil pump regulator (or pressure relief valve) spring has to be suspect. Over the years the spring has likely relaxed a bit or the valve has gunked up.