1) Articulation. Yes, IxS can articulate each wheel independently (to a point,) and that typically makes for better manners and handling on-road. However, the off-road advantage goes to SLA setups. Why? Because when one wheel is raised on SLA, the other is driven downwards - which helps to keep both wheels on the end of the axle planted. While this isn't such a problem with ATVs (most of them weigh around what I do,) when you're horsing two tons around, you need all the help you can get.
2) Simplicity. Less engineering is required, less support elements are required, and that means that suspension designs can be simpler, easier to repair, and easier to modify.
3) Durability. IxS halfshafts tend to be smaller than SLA shafts (Strike one!) and are usually hollow (Strike two! - depending on wall thickness...) They're also exposed to the environment (as mentioned previously,) which means that the coating on them can be stripped by the environment, which allows environmental corrosion to start, which means weak spot! Or, something could hit the shaft, resulting in a crease in the metal, resulting in a weak spot! A spot of corrosion or a crease in a metal member (or a scribe line, or where a saw wandered, or...) may as well be a dashed line saying "Tear Here." Yes, you can bend an SLA shaft, but it's far more work (and you usually have larger problems by then.) The SLA shafts are protected by the axle housing - typically 1/4" wall tubing or better, in truck applications - and there's usually the best part of an inch of air in between. You can bend a tube without wrecking the axle beyond utility - but replace the assembly when you get home. IxS? Replace the halfshaft soonest - meaning on the trail (constant reversed stresses are Hell on members with defects...)
IxS works well on ATVs because they're small and light - and being small, the axle assemblies can be short, which means they don't need as much articulation. Also, I greatly suspect most ATVs aren't used in rockclimbing - so they don't deal with as much off-camber terrain, nor do they really need as much articulation to begin with (someone please correct me if I'm wrong.) There's the pivotal difference - the working length of an ATV axle runs - I think - around 30-36", while a truck axle works with 60" and up. Cutting that lever arm in half (or an offset centre, as with IFS) makes things silly.
Does this make sense, or are you as at sea as you were before? I hope it does help...