Well, I'm not so sure about that...
I've put new lifters on an old cam - as long as you are generous with the assembly lube, and take your time to "run" them in before you get silly, I've put a couple hundred thousand more miles on an engine with a lifter replacement.
New cam + old lifters = wrecked cam, in about an hour. Doesn't matter what else you do to it, you're wrecking a camshaft.
I replaced the lifters on my wife's 89 Limited several years ago (they were clogged up - the engine had arteriosclerosis from the previous owner's use of Pennzoil...) and haven't had any trouble with them since.
Although, before I changed the lifters, I'd take an hour or so to check that all the rocker arm pivot bolts are set to torque, and I'd probably apply LocTite #242 to make sure they stay that way (OK, I'm cranky.) The first couple times I thought I'd be doing lifters, it turned out that checking the rocker bolts was enough to solve the problem (damme if changing lifters on the 242 isn't the J-O-B...)
If you really want to see what's going on, take the valve cover off, get a 3/4" socket and ratchet to fit, and check for freeplay in the pushrods on the closed valves (you should not be able to turn the pushrod with your fingertips.) Turn the engine 180*, and check out the next closed valves. I don't recall the sequence, but you'll end up turning the engine twice...
5-90