I've had these boxes apart - while you can just pull the input shaft gland (where the shaft from the steering column comes in) and change it, it's a pain and the seal tends to get chewed up on those splines if you're not real careful... A "face spanner" wrench is required.
If it's the Pitman seal (the one at the bottom - the output end) it's a little easier - as I recall, you can get away with pulling the Pitman arm, taking out the snapring, and drilling a small hole in the seal ring so you can grab it and pull it loose. Install the new one, install the snapring, and check.
Still, it's usually a LOT easier to just get a new steering box and not worry about it at all. I typically use A1Cardone remans - have for years. It would take you about as long to change the box as it would to replace the seal - and you won't have to worry about it as much.
Y'ask me, you're really better off just changing the box - I typically will only change the seal if that's what I need to get me back to civilisation, or carry me through a catastrophic failure if I need to wait to get a new box...
5-90