I've done it a few times. Tire treads and the like are unreliable reference points. RCP Phx hints at the correct technique. The best way to do this if you can is to take a big piece of chalk, lift the wheel off the ground just enough to spin, and chalk the tread (it doesn't matter where, just on the flat part). Now take a block of wood with a nail in it, and the head of the nail snipped off, to make a scratching tool. with the tire just off the ground, run the block along the ground so that the nail hits the chalked tread, and rotate the tire so it scribes a sharp line in the chalk. Do the same on the other side, and you now have a precise set of marks to measure from. Back in the old days, garages had a manufactured scratcher with a cast iron stand and the point on a spring-loaded pivot, but the block works if you're careful. If possible, and if you're on a smooth floor, mount a stick on feet, and use that as your measuring device rather than a tape measure, and it will not be subject to as much error from sag and the like. Again, once upon a time, garages had these sticks on feet, with pointers that slid along them, and the closer you get to this kind of setup, the better you'll do.
I've aligned a couple of Jeeps and had even front tire wear for the life of a good set of tires, so I think it's safe to say it can be done.