The RENIX system will run fine without the EGR - mine only works for about a month every other year anyhow. I wish I could just delete it entirely - HC and CO are rather lower, and if NOx picks up as a result, I have no trouble (and would prefer) installing a water fogger or a water/alcohol fogger anyhow, since it works better and keeps the engine cleaner. Crapping up the intake doesn't seem like a good way to reduce emissions, y'ask me.
If you need to maintain the EGR valve (because you're in an area subject to the Air Police,) you can have a bung welded on the exhuast manifold, and rerun the tube.
I'd not expect the HO exhaust to fit right up to the RENIX head - I know the intakes are different, and the exhaust ports were reduced on the #0331 head (1999 or so,) but I don't recall exhaust differences between the #2686 (RENIX) head and the #7130/#0630 (1991-1995 and 1996-1998/9) heads. I haven't been able to collect any samples yet, either.
There are RENIX headers out there, just expect to spend a little more on them, because there are fewer RENIX engines than HO out there...
As long as you're about it, replace as much exhaust hardware as you can with brass or bronze - it will save you a lot of trouble later. Manifold bolts are 3/8"-16x1.25" (I just ordered a batch of hex heads...) and most exhaust clamps take a 5/16"-18 or 3/8"-16 nut. The collector nuts are 3/8"-16, and brass nuts should be readily available at hardware stores or boating supply shops.
Using brass and bronze eliminates the possibility of the nut seizing on the stud/bolt/whatever, and it has no trouble with the heat. I've been using brass/bronze hardware on exhaust for a good twenty years now...
5-90