Running the 180 degree thermostat won't change the final temperature of the engine. Running a too cold thermostat will extend warm up times, will waste fuel, will lead to fuel contamination in the oil, and might contribute to scoring the cylinders/pistons as the fuel washes away lubrication. That amounts to a whole lot of bad for doing the wrong thing for the wrong reason.
IF you are running hot with the proper thermostat in the cooling system you have a problem with the cooling system that needs to be taken care of.
Your wife's lack of heat may be due to the distance she is driving with that craptastic 180 degree thermostat in there.